500mg one to three times daily.
Up to 1200mg twice a day have shown significant reductions in the pain and tenderness of chronicFibromyalgia symptoms.
Malic Acid has traditionally been used for fibromyalgia, chronic fatigue syndrome (CFS), stress, tender points, pain, persistent fatigue, muscular pain, arthritic-like symptoms, and for performance and recovery from exercise.
Studies have shown that malic acid, when given with magnesium, resulted in a 41% reduction in tender points after four weeks and 76% after eight weeks. In some cases, noticeable improvement was evident in as little as forty-eight hours.
Current research does not indicate any adverse effects from the use of malic acid in moderate amounts.
At the time of writing, there were no well-known drug interactions with malic acid.
Fibromyalgia – Co Enzyme Q10, pycnogenol/grape seed, B complex, Cal/Mag/Zn